This minor basilica is said to be one of the oldest churches built in Rome dedicated to the Virgin Mary. It dates from the 4th century and it is also one of the first churches that openly celebrated mass during this time.
The church was restored in the 5th and 8th centuries, then in 1140 Pope Innocent II ordered the demolition of the church and removal of the tomb of the antipope Anacletus II, then commissioned the rebuilding using twenty-two granite columns thought to be from the Baths of Caracalla.
The facade was restored by Carlo Fontana in 1702. The facade mosaics are attributed to Pietro Cavallini.
The apse is decorated by mosaics from the 12 century and the 13th century mosaic panels are also by Pietro Cavallini.
The apse ceiling panels depicting the Assumption of the Virgin were by Domenichino and date to 1617.
The church is open daily from 8pm until 8pm.